Search on: 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES 
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Descriptor English:   3-Phosphoinositide-Dependent Protein Kinases 
Descriptor Spanish:   Proteínas Quinasas Dependientes de 3-Fosfoinosítido 
Descriptor Portuguese:   Proteínas Quinases Dependentes de 3-Fosfoinositídeo 
Synonyms English:   3-Phosphoinositide Dependent Protein Kinase-1
3-Phosphoinositide Dependent Protein Kinase-2
3-Phosphoinositide-Dependent Kinase 1 (PDK1)
3-Phosphoinositide-Dependent Protein Kinase
3-Phosphoinositide-Dependent Protein Kinase-1
3-Phosphoinositide-Dependent Protein Kinase-2
PtdIns(3,4,5)P3-Dependent Protein Kinase-1
3 Phosphoinositide Dependent Protein Kinase
3 Phosphoinositide Dependent Protein Kinase 1
3 Phosphoinositide Dependent Protein Kinase 2
3 Phosphoinositide Dependent Protein Kinases
Kinase, 3-Phosphoinositide-Dependent Protein
Kinase-1, 3-Phosphoinositide-Dependent Protein
Kinase-2, 3-Phosphoinositide-Dependent Protein
Kinases, 3-Phosphoinositide-Dependent Protein
Protein Kinase, 3-Phosphoinositide-Dependent
Protein Kinase-1, 3-Phosphoinositide-Dependent
Protein Kinase-2, 3-Phosphoinositide-Dependent
Protein Kinases, 3-Phosphoinositide-Dependent  
Tree Number:   D08.811.913.696.620.682.700.745
Definition English:   Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the production of the SECOND MESSENGERS, phosphatidylinositol 3,4,-biphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3). 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55307 
Unique Identifier:   D064413 

Occurrence in VHL:
 

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